A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/72 (2006.01) A61K 9/51 (2006.01) A61K 47/14 (2006.01) A61K 47/24 (2006.01) A61K 47/28 (2006.01) A61K 47/32 (2006.01) A61K 9/16 (2006.01)
Patent
CA 2477592
Remarkable effects are established by providing a powdery composition for inhalation, which comprises a crystalline physiologically active substance and a biocompatible electrostatic aggregation inhibitor, has a high safety and a high stability and achieves excellent delivery properties toward lungs, by a convenient process. By further selecting a hydrophobic substance, sustained release properties appropriate for the characteristics of the physiologically active substance can be imparted to the composition.
L'invention concerne une composition en poudre pour inhalation produisant des effets remarquables, qui renferme une matière cristalline physiologiquement active et un anti-agglomérant électrostatique biocompatible ; cette composition est sans danger, présente une grande stabilité et d'excellentes propriétés d'administration aux poumons, et peut être produite grâce à un procédé adéquat. La sélection d'une matière hydrophobe permet en outre de conférer à ladite composition des propriétés de libération prolongée, appropriées du point de vue des caractéristiques de la matière physiologiquement active.
Katsuma Masataka
Kawai Hitoshi
Mizumoto Takao
Astellas Pharma Inc.
Dennison Associates
Yamanouchi Pharmaceutical Co. Ltd.
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