Poxviral oncolytic vectors

Details Poxviral oncolytic vectors Poxviral oncolytic vectors

C - Chemistry, Metallurgy

07

K

C07K 14/005 (2006.01) A61K 39/275 (2006.01) C07K 14/065 (2006.01)

Patent

CA 2705869

The present invention relates to a poxvirus comprising a defective F4L and/or I4L gene, to composition comprising such poxvirus and to the methods and use of such compositions and poxviruses for therapeutic purposes, and more particularly for the treatment of cancer.

La présente invention concerne un poxvirus comprenant un gène F4L et/ou un gène I4L défectueux, une composition comprenant ledit poxvirus, des procédés et l'utilisation de telles compositions et de tels poxvirus à des fins thérapeutiques, et plus particulièrement pour le traitement du cancer.

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