Poxviridae treatment

Details Poxviridae treatment Poxviridae treatment

A - Human Necessities

61

K

A61K 39/39 (2006.01) A61K 38/17 (2006.01) A61K 39/275 (2006.01) A61K 48/00 (2006.01) A61P 31/20 (2006.01)

Patent

CA 2673757

A vaccine composition for combating Pox viridae viral infections in living organisms such as mammals (including humans) comprises TAP-1 and/or TAP-2 to augment the antigen processing capability of infected cells and hence their immunogenicity. The composition may be used alone or, preferably, as an immunogenicity-enhancing adjuvant with pox antigen-based vaccine in treatment or prophylaxis especially of smallpox viral infections.

L'invention concerne une composition de vaccin pour combattre des infections virales à Poxviridae chez des organismes vivants tels que les mammifères (y compris, les êtres humains). La composition de vaccin comprend TAP-1 et/ou TAP-2 pour augmenter l'aptitude au traitement des antigènes de cellules infectées et par conséquent leur immunogénicité. La composition peut être utilisée seule ou, de préférence, en tant qu'adjuvant améliorant l'immunogénicité avec un vaccin à base d'antigène du virus Pox dans le traitement ou la prophylaxie, notamment d'infections virales de la variole.

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