C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 19/00 (2006.01) C12N 9/16 (2006.01) C12N 9/99 (2006.01) C12N 15/09 (2006.01) C12N 15/62 (2006.01) C12N 15/63 (2006.01) A61K 38/16 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2685592
The invention relates to phosphatase ligands and polyligands. In particular, the invention relates to ligands, homopolyligands, and heteropolyligands that modulate PP1 activity. The ligands and polyligands are utilized as research tools or as therapeutics. The invention includes linkage of the ligands, homopolyligands, and heteropolyligands to a cellular localization signal, epitope tag and/or a reporter. The invention also includes polynucleotides encoding the ligands and polyligands.
L'invention concerne des ligands de phosphatase et des polyligands. L'invention concerne, en particulier, des ligands, des homopolyligands, et des hétéropolyligands qui modulent l'activité PP1. Les ligands et les polyligands sont utilisés comme outils de recherche ou comme substances thérapeutiques. L'invention comprend la liaison des ligands, des homopolyligands et des hétéropolyligands à un signal de localisation cellulaire, un marqueur d'épitope et/ou d'un rapporteur. L'invention comprend également des polynucléotides codant les ligands et les polyligands.
Atzel Amy
Bachinsky David
Reed Thomas
Tretiakova Anna
Borden Ladner Gervais Llp
Intrexon Corporation
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