Pp14 fusion proteins and methods for making and using the same

Details Pp14 fusion proteins and methods for making and using the same Pp14 fusion proteins and methods for making and using the same

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 16/46 (2006.01) C12N 1/00 (2006.01) C12N 15/12 (2006.01) C12N 15/13 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2395198

Novel fusion proteins comprising PP14 are disclosed. The fusion proteins retain the immunoregulatory function of native PP14, but offer significant advantages. Methods for using the fusion proteins, and sequence encoding the same, in the treatment of immune system diseases and disorders are therefore also disclosed, as are methods for recombinant production of the present fusion proteins.

L'invention concerne de nouvelles protéines hybrides comprenant la PP14. Ces protéines conservent la fonction immunorégulatrice de la PP14 native, tout en offrant des avantages importants. L'invention concerne également des procédés d'utilisation des protéines hybrides, ainsi que la séquence les codant, dans le traitement de maladies et troubles du système immunitaire, et des procédés de production par recombinaison de ces protéines hybrides.

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