A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/17 (2006.01) A61K 31/00 (2006.01) A61K 31/4439 (2006.01) A61K 48/00 (2006.01) A61P 9/10 (2006.01) A61P 25/28 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C12N 15/11 (2006.01) G01N 33/50 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2378462
A method of preventing or reducing foam cell development from macrophages, or removing foam cells, in a patient, the method comprising administering to the patient an effective amount of an inhibitor of PPAR.delta. activity. A method of preventing or treating a vascular disease associated with plaque formation and/or thrombotic blockage of the blood vessels in a patient, the method comprising administering to the patient an effective amount of an inhibitor of PPAR.delta. activity.
L'invention concerne un procédé de prévention ou de réduction du développement de cellules spumeuses à partir de macrophages, ou d'élimination de telles cellules chez un patient, ce procédé consistant à administrer à ce patient une dose efficace d'un inhibiteur de l'activité de PPAR.delta.. L'invention concerne également un procédé de prévention ou de traitement d'une maladie vasculaire associée à la formation de plaquettes et/ou au blocage thrombotique d'un vaisseau sanguin, chez un patient, ce procédé consistant à administrer à ce patient une dose efficace d'un inhibiteur de l'activité de PPAR.delta..
Palmer Colin Neil Alexander
Vosper Helen
Wolf Charles Roland
Gowling Lafleur Henderson Llp
The University Of Dundee
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