Ppar-gamma agonists for the induction of cationic...

Details Ppar-gamma agonists for the induction of cationic... Ppar-gamma agonists for the induction of cationic...

A - Human Necessities

61

K

A61K 31/136 (2006.01) A61K 31/166 (2006.01) A61K 31/196 (2006.01) A61K 31/343 (2006.01) A61K 31/357 (2006.01) A61K 31/4439 (2006.01) A61K 31/47 (2006.01) A61K 31/606 (2006.01) A61K 31/609 (2006.01) A61P 1/00 (2006.01) A61P 1/02 (2006.01) A61P 1/04 (2006.01) A61P 11/02 (2006.01) A61P 17/00 (2006.01) G01N 33/94 (2006.01)

Patent

CA 2678159

Rosiglitazone, 5-ASA or structurally analogous Compounds according to the general formula (I): or Compounds according to the general formula (Ia): For the induction of CAMP expression in tissues having PPAR-gamma receptors. Such tissues include epithelia or mucosae tissue having PPAR-gamma receptors and of particular interest .iota.s CAMP expression in the gut

L'invention concerne la rosiglitazone, le 5-ASA, des composés structurellement analogues de formule (I), ou des composés de formule (Ia), destinés à induire l'expression de CAMP dans des tissus présentant des récepteurs de PPAR-gamma. De tels tissus comprennent des tissus épithéliaux ou mucosaux présentant des récepteurs de PPAR-gamma. L'invention concerne en particulier l'expression de CAMP dans l'intestin.

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