Ppar modulators

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 59/68 (2006.01) A61K 31/095 (2006.01) A61K 31/19 (2006.01) A61K 31/44 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) A61P 9/00 (2006.01) C07C 251/24 (2006.01) C07C 321/28 (2006.01) C07D 213/64 (2006.01) C07D 213/69 (2006.01) C07D 213/72 (2006.01)

Patent

CA 2536089

The present invention is directed to a compound of formula I, or a pharmaceutically acceptable salt, solvate, hydrate or stereoisomer thereof, which is useful in treating or preventing disorders mediated by a peroxisome proliferator activated receptor (PPAR) such as syndrome X, type II diabetes, hyperglycemia, hyperlipidemia, obesity, coagaulopathy, hypertension, arteriosclerosis, and other disorders related to syndrome X and cardiovascular diseases.

L'invention se rapporte à un composé de la formule I, ou un à un sel, un hydrate ou un isomère optique pharmaceutiquement acceptable de celui-ci, qui est utile dans le traitement ou la prévention de troubles médiés par un récepteur activé de la prolifération des péroxysomes (PPAR), tel que le syndrome X, les diabètes du type II, l'hyperglycémie, l'hyperlipidémie, l'obésité, la coagulopathie, l'hypertension, l'artériosclérose, et d'autres troubles liés au syndrome X et aux maladies cardio-vasculaires.

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