Practical, cost-effective synthesis of ubiquinones

C - Chemistry – Metallurgy – 07 – C

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C07C 50/28 (2006.01) A61K 31/122 (2006.01)

Patent

CA 2548250

The present invention provides a convergent method for the synthesis of ubiquinones and ubiquinones analogues. Also provided are precursors of ubiquinones and their analogues that are useful in the methods of the invention, The invention further provides an improved method for the carboalumination of alkyne substrates.

L'invention porte sur un procédé convergent de synthèse d'ubiquinones et d'analogues des ubiquinones. L'invention concerne également des précurseurs des ubiquinones et de leurs analogues, qui sont utilisés selon les procédés de l'invention. L'invention se rapporte en outre à un procédé amélioré de carboalumination de substrats alkyne.

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