C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 19/073 (2006.01) C07D 405/04 (2006.01) C07H 19/06 (2006.01) C07H 19/16 (2006.01) C07H 19/173 (2006.01)
Patent
CA 2074184
2074184 9110670 PCTABS00006 A method for the preparation of 2'-deoxynucleosides and 2',3'-dideoxy-2',3'-didehydronucleosides that includes the step of reacting a nucleoside having hydroxyl groups in the 2' and 3' positions with a mixture of acyl bromide or chloride and HX, wherein X is Br or Cl, at moderate temperature, to give a haloacyl nucleoside derivative that can be deprotected and reduced to form the desired compound.
Bereskin & Parr
Chu Chung K.
University Of Georgia Research Foundation Inc.
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