C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 15/252 (2006.01) A61K 31/70 (2006.01) C07H 15/24 (2006.01) C07H 15/244 (2006.01)
Patent
CA 2052020
The present invention relates to new antifungal compounds having the formula (see formula I) wherein R1 is hydrogen, methyl, or hydroxymethyl; R2 and R3 are independently selected from the group consisting of hydrogen and C1-5 alkyl; and R4 is selected from the group consisting of .beta.-L-xylosyl, .beta.-D- ribosyl, .alpha.-L-arabinosyl, .beta.-D-chinovosyl, .beta.-D-fucosyl, and .beta.-D-glucosyl; with the proviso that when R1 as methyl or hydroxymethyl, and one of R2 or R3 is methyl, R4 is not .beta.-D-glucosyl; or a pharmaceutically acceptable salt thereof.
Aburaki Shimpei
Naito Takayuki
Yamashita Haruhiro
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
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