A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/00 (2006.01) C07K 14/435 (2006.01)
Patent
CA 2681132
The invention relates to a peptide having a length of no more than 100 amino acids and comprising at least 19 contiguous amino acids from the amino acid sequence of the human PRAME protein, wherein the peptide comprises at least one HLA class II epitope and at least one HLA class I epitope from the amino acid sequence of the human PRAME protein and to its use as such or in a composition as a medicament for the treatment and/or prevention of cancer.
L'invention concerne un peptide dont la longueur n'excède pas 100 acides aminés, et qui comprend au moins 19 acides aminés contigus provenant de la séquence d'acides aminés de la protéine PRAME humaine, le peptide comportant au moins un épitope de classe II HLA et au moins un épitope de classe I HLA provenant de la séquence d'acides aminés de la protéine PRAME humaine, et son utilisation telle quelle dans une composition comme médicament pour le traitement et/ou la prévention du cancer.
Drijfhout Jan Wouter
Griffioen Marieke
Kessler Jan
Melief Cornelis Johannes Maria
Academisch Ziekenhuis Leiden H.o.d.n. Lumc
Gowling Lafleur Henderson Llp
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