A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/20 (2006.01) A61K 9/28 (2006.01) A61K 31/22 (2006.01) A61K 31/225 (2006.01) A61P 3/10 (2006.01) A61P 9/00 (2006.01)
Patent
CA 2497896
The present invention relates to formulations comprising a therapeutically effective amount of pravastatin, or a pharmaceutically acceptable salt thereof. The present formulations are designed to prevent inactivation of pravastatin in the stomach, limit systemic exposure of the body to pravastatin, and maximize hepatic-. specific absorption of the drug. The formulations of the present invention are particularly useful for treating and/or preventing conditions that are benefited by decreasing levels of lipids and/or cholesterol in the body.
La présente invention concerne des formulations contenant une quantité thérapeutiquement efficace de pravastatin ou leurs sels pharmaceutiquement acceptables. Ces formulations permettent d'empêcher l'inactivation du pravastatin dans l'estomac, l'exposition systémique limite de l'organisme au pravastatin et de maximiser l'absorption spécifique hépathique du médicament. Ces formulations sont particulièrement utiles pour traiter et/ou prévenir les états qui sont améliorés par la baisse des niveaux de lipides et/ou de cholestérol dans l'organisme.
Butler Jackie
Devane John
Stark Paul
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Biovail Laboratories Inc.
Circ Pharma Research And Development Limited
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