Prazole derivatives and salts thereof and use of same

Details Prazole derivatives and salts thereof and use of same Prazole derivatives and salts thereof and use of same

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/4439 (2006.01) A61P 1/04 (2006.01)

Patent

CA 2603290

The present invention discloses new derivatives of formula I or II, and the salt thereof, wherein, the R1 presents the low alkyl or halogen substituted low alkyl; R2 presents the straight or branched C1-C4 alkyl; R3 presents the hydrogen or alkali metal such as lithium, sodium, potassium etc, or alkali earth metal such as magnesium, calcium etc. The compound of formula I or II, or the pharmaceutically acceptable salt thereof, can be used to treat gastrelcoma.

Cette invention concerne de nouveaux dérivés de formule I ou II, et leur sel, dans lesquelles R1 représente un alkyle inférieur ou un alkyle inférieur substitué par un halogène ; R2 représente un alkyle en C1 à C4 linéaire ou ramifié ; R3 représente un hydrogène ou un métal alcalin tel que le lithium, le sodium, le potassium, etc., ou un métal alcalino-terreux tel que le magnésium, le calcium, etc. Le composé de formule I ou II, ou son sel pharmaceutiquement acceptable, peut être utilisé pour le traitement du gastrelcoma.

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