Prebiotic and probiotic compositions and methods for their...

A - Human Necessities – 01 – N

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A01N 63/00 (2006.01) A23L 1/30 (2006.01) A61K 9/50 (2006.01) A61K 31/702 (2006.01) A61K 31/736 (2006.01) A61K 33/08 (2006.01) A61K 35/74 (2006.01)

Patent

CA 2447376

Microencapsulated and/or enteric coated composition containing a mixture of probiotics, prebiotics and ammoniaphilic bacteria with high urease activity with or without sorbents with specific adsorption afffinities for uremic toxins such as creatinine, uric acid, phenol, indoles, middle molecular weight molecules and inorganic phosphate and water absorbents are provided. Also provided are methods of allevating symptoms of uremia in a patient which comprises administering orally to a patient suffering from uremia a microencapsulated and/or enteric-coated composition

L'invention concerne une composition à enrobage entérique et/ou en microcapsules contenant un mélange de bactéries probiotiques, prébiotiques et ammoniaphiliques à activité d'urase élevée, avec ou sans sorbants, présentant des affinités d'adsorption spécifiques pour des toxines urémiques telles que la créatinine, l'acide urique, le phénol, les indoles, les molécules présentant un poids moléculaire moyen et les phosphates inorganiques ainsi que les absorbants d'eau. Elle concerne aussi des procédés pour atténuer les symptômes d'urémie chez un patient qui consiste à administrer par voie orale une composition à enrobage entérique et/ou en microcapsules à un patient souffrant d'urémie.

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