Predicting survival of patients with squamous cell carcinoma

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C12Q 1/02 (2006.01) G01N 33/48 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2317690

The invention relates to methods of determining a relative probability of survival for a subject with squamous cell carcinoma by obtaining a biological sample from a subject with squamous cell carcinoma; detecting a level of maspin gene expression in the biological sample; and comparing the level with a threshold level of maspin gene expression. A level of maspin gene expression in the biological sample above the threshold level indicates a relatively high probability of survival, or a level of maspin gene expression in the biological sample below the threshold level indicates a relatively low probability of survival.

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