C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2714393
The present invention provides for methods of identifying a dog carrying a major genetic risk factor in the SOD1 gene for degenerative myelopathy, a potential model for human amyeotrophic lateral sclerosis. Also provided a methods of early diagnosis, treatment and breeding based on the presence or absence of the marker.
La présente invention concerne des procédés permettant d'identifier un chien porteur d'un facteur de risque génétique majeur au niveau du gène SOD1 codant pour la myélopathie dégénérative, un modèle potentiel de la sclérose latérale amyotrophique humaine. Des procédés de diagnostic précoce, de traitement et de sélection basés sur la présence ou sur l'absence du marqueur sont également décrits.
Coates Joan R.
Johnson Gary S.
Linblad-Toh Kerstin
Wade Claire
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
The Curators Of The University Of Missouri
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