Prediction of antiviral therapy response

Details Prediction of antiviral therapy response Prediction of antiviral therapy response

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2728816

The application relates to methods for determining whether or not antiviral therapies will be effective. In particular, the present application provides a method using miRNA, e.g. miR- 122 or miR-296-5p, for determining the likelihood that a subject having a viral infection of the liver will be responsive to antiviral therapy that includes stimulation of Interferon (IFN) activity, and kits for the performance of said determination.

La présente invention concerne des procédés consistant à déterminer si des thérapies antivirales seront efficaces ou non. En particulier, la présente invention concerne un procédé utilisant l'ARNmi, par exemple le miR-122 ou le miR-296-5p, afin de déterminer la probabilité, pour un sujet ayant une infection virale du foie, de répondre à une thérapie antivirale qui comprend la stimulation de l'activité de l'interféron (IFN), et des kits pour effectuer ladite détermination.

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