Prediction of bone marrow toxicity

Details Prediction of bone marrow toxicity Prediction of bone marrow toxicity

C - Chemistry, Metallurgy

12

Q

C12Q 1/48 (2006.01)

Patent

CA 2714183

The likelihood that a compound will exhibit bone marrow toxicity in an in vivo assay predicted by the ability of the compound to inhibit at least eight kinases from a selected group.

La présente invention concerne un procédé selon lequel la probabilité quun composé va présenter une toxicité de la moelle osseuse dans un dosage in vivo est prédite grâce à la capacité du composé dinhiber au moins huit kinases à partir dun groupe sélectionné.

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