Pregnane 3,20 diol mono- and di-sulphates

C - Chemistry – Metallurgy – 07 – J

Patent

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C07J 31/00 (2006.01) A61K 31/57 (2006.01) C07J 7/00 (2006.01)

Patent

CA 2289095

This invention provides a compound having formula (I) wherein R and R1 are each, independently, hydrogen or SO3-X+; X+ is alkali metal, alkaline earth metal, ammonium, alkylammonium containing 1-6 carbon atoms, or dialkylammonium containing 1-6 carbon atoms in each alkyl group, or trialkylammonium containing 1-6 carbon atoms in each alkyl group; with the proviso that R and R1 are not both hydrogen, which is useful as a progestational agent.

La présente invention concerne un composé de la formule: dans laquelle R et R?1¿ sont chacun, indépendamment, hydrogène ou SO¿3??-¿X?+¿; X?+¿ est un métal alcalin, un métal alcalino-terreux, un ammonium, un alkylammonium renfermant de 1 à 6 atomes de carbone, ou un dialkylammonium renfermant de 1 à 6 atomes de carbone dans chaque groupe alkyle, ou un trialkylammonium renfermant de 1 à 6 atomes de carbone dans chaque groupe alkyle; à condition que R et R?1¿ ne soient pas tous deux hydrogène, ledit composé étant utilisé comme progestatif.

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