Prenylated bisphosphonates as anti-tuberculosis agents

C - Chemistry – Metallurgy – 07 – F

Patent

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Details

C07F 9/38 (2006.01) A61K 31/663 (2006.01) A61P 31/06 (2006.01) C07F 9/572 (2006.01)

Patent

CA 2755975

The invention provides methods to treat a mycobacterium infection and methods to inhibit mycobac-terial polyprenyl pyrophosphate synthesis with a com-pound of formula I. The invention also provides novel compounds of formula I as well as salts and prodrugs thereof.

La présente invention concerne des méthodes de traitement d'une infection par une mycobactérie et des méthodes d'inhibition de la synthèse de pyrophosphate de polyprényle mycobactérien à l'aide d'un composé de formule I. La présente invention concerne également de nouveaux composés de formule I ainsi que leurs sels et promédicaments. [insérer la formule I]

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