Preparation and application of anti-tumor bifunctional...

A - Human Necessities – 61 – K

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A61K 39/395 (2006.01) C07H 21/04 (2006.01) C07K 16/00 (2006.01) C12N 15/00 (2006.01)

Patent

CA 2528595

Provided herein is a chimeric protein, which chimeric protein comprises a Flt3 ligand, or a biologically active fragment thereof, and a proteinuous or peptidyl tumoricidal agent, and uses thereof, particularly in the treatment of malignancy.

L'invention porte sur une protéine chimère, cette protéine chimère comprenant un ligand Flt3, ou un fragment de celui-ci biologiquement actif, et un agent tumoricide protéique ou peptidyl, et sur des utilisations associées, notamment dans le traitement des tumeurs malignes.

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