Preparation and therapeutic applications of...

C - Chemistry – Metallurgy – 07 – D

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C07D 453/02 (2006.01) A61K 31/439 (2006.01) A61P 3/00 (2006.01) A61P 25/02 (2006.01) A61P 25/04 (2006.01) A61P 25/06 (2006.01) A61P 25/28 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2749123

The present invention relates to compounds that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central nervous system (CNS).

La présente invention porte sur des composés qui se lient aux récepteurs nicotiniques neuronaux d'acétylcholine et modulent sont activité, sur des traitements de préparation de ces composés, sur des compositions pharmaceutiques contenant ces composés, et sur des procédés d'utilisation de ces composés pour traiter une grande diversité de conditions et de troubles, comprenant ceux associés au dysfonctionnement du système nerveux central (SNC).

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