Preparation and use of fluorescent benzothiazole derivatives

Details Preparation and use of fluorescent benzothiazole derivatives Preparation and use of fluorescent benzothiazole derivatives

C - Chemistry, Metallurgy

07

D

167/43, 150/8, 2

C07D 277/62 (2006.01) C07D 277/64 (2006.01) C07D 277/68 (2006.01) C07F 9/6541 (2006.01) C12Q 1/34 (2006.01) C12Q 1/42 (2006.01) G01N 31/22 (2006.01) G01N 33/58 (2006.01)

Patent

CA 1340749

A compound represented by: Image wherein: (a) at least one of the carbons of any of positions 4, 5, 6 or 7 is linked to a chemical moiety containing an anion group which is attached to the benzene ring; (b) the carbon at position 2 is linked to a chemical moiety, X, comprised of at least 2 atoms; (c) a nitrogen atom is located at position 3; (d) a sulfur atom is located at position 1; and (e) a chemical moiety attached to said anion group of subpart (a) which inhibits fluorescence; wherein upon removal of said chemical moiety of subpart (e), the resulting compound is fluorescent. These compounds are useful in fluorescent substrates and in biological assays.

605044

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