Preparation and use of triphenyl methanethiol-35s

Details Preparation and use of triphenyl methanethiol-35s Preparation and use of triphenyl methanethiol-35s

C - Chemistry, Metallurgy

07

B

260/287, 260/552

C07B 59/00 (2006.01) C07C 321/20 (2006.01) C07C 323/51 (2006.01) C07D 215/12 (2006.01)

Patent

CA 2011217

1/FSC4 17862 TITLE OF THE INVENTION PREPARATION AND USE OF TRIPHENYL METHANETHIOL-35S ABSTRACT OF THE DISCLOSURE Disclosed herein are /35S/-labelled compound of the formula (I): (C6H5)3C35SH and process therefor. This Compound (I) is useful as an intermediate for the introduction of sulfur isotope into a variety of compounds. For example, it is useful in the introduction of sulfur isotope into important compounds such as 6-mercaptopurine, 5-[3-(2-(7-chloroquinolin-2-yl)ethenyl)pheny1]-8- dimethylcarbamyl-4,6-dithioactanoic acid, a potent antagonist of leukotriene D4; thiophosphoric acid derivatives, photo affinity reagents and the like.

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