Preparation based on an antibody directed against a...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/28 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 16/30 (2006.01)

Patent

CA 2488885

The invention relates to the use of a preparation based on -an antibody directed against a tumor-associated glycosylation for preparing a medicament for the prophylactic and/or therapeutic treatment for the reduction or inhibition, respectively, of the growth of tumor cells in a cancer patient, as well as to a pharmaceutical preparation containing an antibody directed against a tumor-associated glycosylation. Moreover, the invention relates to a preparation for pharmaceutical and/or diagnostic use, a diagnostic method and an agent for determining the risk of metastasis formation in a cancer patient, as well as a method of producing a preparation based on a body fluid or tissue, in each case using the antibody directed against a tumor-associated glycosylation.

La pr~sente invention concerne l'utilisation d'une pr~paration ~ base d'un anticorps dirig~ contre une glycolysation associ~e ~ une tumeur, pour pr~parer un m~dicament de pr~vention et/ou de traitement qui permet la r~duction ou l'inhibition, respectivement, de la croissance de cellules tumorales chez un patient atteint d'un cancer, ainsi qu'une pr~paration pharmaceutique contenant un anticorps dirig~ contre une glycolysation associ~e ~ une tumeur. De plus, l'invention concerne une pr~paration pour utilisation pharmaceutique et/ou diagnostique, un proc~d~ de diagnostic et un agent pour d~terminer le risque de formation de m~tastases chez un patient atteint d'un cancer, ainsi qu'un proc~d~ pour produire une pr~paration ~ base d'un fluide ou tissu corporel, qui dans chaque cas fait intervenir l'utilisation d'un anticorps dirig~ contre une glycolysation associ~e ~ une tumeur.

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