Preparation for 1,4-benzodiazepines

Details Preparation for 1,4-benzodiazepines Preparation for 1,4-benzodiazepines

C - Chemistry, Metallurgy

07

D

260/240.4

C07D 243/28 (2006.01) C07D 243/24 (2006.01)

Patent

CA 1049514

ABSTRACT OF THE DISCLOSURE A novel process for producing 1,4-benzodiazepine derivatives of the formula (I), Image (I) wherein X is halogen, R1 is C1-C5 alkyl, and R2 is C1-C5 alkyl, and their pharmaceutically acceptable salts, which are useful as medicaments. These compounds (I) may be obtained by reacting a compound of the formula (II), Image (II) wherein X, R1 and R2 are as defined above, with a halogen or a hypohalogenous acid salt in the presence of a base.

192533

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