Preparation for nasal administration

Details Preparation for nasal administration Preparation for nasal administration

A - Human Necessities

61

K

A61K 31/5575 (2006.01) A61K 9/00 (2006.01) A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 31/557 (2006.01) A61K 47/32 (2006.01) A61K 47/38 (2006.01) A61P 25/20 (2006.01)

Patent

CA 2389869

A pernasal preparation containing as the active ingredients a prostaglandin of the following general formula or a pharmaceutically acceptable salt thereof and a water-soluble polymer: wherein X is halogeno; R1 is C3-10 cycloalkyl, C3- 10 cycloalkyl substituted with C1-4 alkyl, or C4-13 cycloalkylalkyl; R2 is hydrogen, C1-10 alkyl, or C3-10 cycloalkyl; m is an integer of 0 to 3; and n is an integer of 1 to 4.

Préparation s'administrant par voie nasale renfermant en tant qu'ingrédient actif une prostaglandine de formule (I) ou un sel pharmaceutiquement acceptable de cette dernière et un polymère soluble dans l'eau. Dans la formule (I), X représente halogéno, R?1¿ représente cycloalkyle C¿3-10?, cycloalkyle C¿3-10? substitué par alkyle C¿1-4?, ou cycloalkylalkyle C¿4-13 ?; R?2¿ représente hydrogène, alkyle C¿1-10? ou cycloalkyle C¿3-10 ?; m représente un entier compris entre 0 et 3 ; et n représente un entier compris entre 1 et 4. Formule (I)

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