Preparation for substitution therapy, containing at least...

A - Human Necessities – 61 – K

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A61K 31/57 (2006.01) A61K 31/565 (2006.01)

Patent

CA 2171460

The invention relates to a preparation for substitution therapy and oral contraception comprising at least one progestogen and at least one estrogen in which the estrogen dose varies with a periodicity such that blood loss is substantially avoided, wherein the periodicity is preferably less than 10 days, more preferably less than 7 days, such as preparations containing the progestogen and/or estrogen in an oral, transdermal, parenteral and/or implantable application form.

L'invention concerne une préparation pour thérapie de substitution et de contraception orale contenant au moins un progestogène et au moins un oestrogène, dans laquelle la dose d'oestrogène varie avec une périodicité permettant d'éviter sensiblement l'apparition de saignements, la périodicité étant de préférence inférieure à 10 jours et notamment à 7 jours. Ces préparations contenant le progestogène et/ou l'oestrogène sont administrées par voie orale, transdermique, parentérale et/ou peuvent être implantées.

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