Preparation for the treatment of nasal hypersecretion

A - Human Necessities – 61 – K

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A61K 31/435 (2006.01)

Patent

CA 1131131

ABSTRACT OF THE DISCLOSURE The invention is a pharmaceutical composition for topical applica- tion to the nose to combat nasal hypersecretion, which comprises a quater- nary tropane alkaloid derivative with atropine-like activity, i.e. vagus blocking activity, and a pharmaceutically acceptable carrier or diluent. The preferred quaternary tropane alkaloid derivative is N-isopropyl nortro- pine tropic acid ester methobromide.

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