Preparation of 1-n-[.omega.-amino-.alpha.-...

Details Preparation of 1-n-[.omega.-amino-.alpha.-... Preparation of 1-n-[.omega.-amino-.alpha.-...

C - Chemistry, Metallurgy

07

H

260/210

C07H 23/00 (2006.01)

Patent

CA 1105452

ABSTRACT OF THE DISCLOSURE An improved process for the preparation of 1-N- [.omega.-amino-.alpha.-hydroxyalkanoyl] aminoglycoside antibiotics comprises acylating a polysilylated aminoglycoside anti- biotic in a substantially anhydrous organic solvent with an acylating derivative of an .omega.-amino-.alpha.-hydroxyalkanoic acid.

370572

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