Preparation of 1-n¬.omega.-amino-.alpha.-hydroxyalkanoyl|...

Details Preparation of 1-n¬.omega.-amino-.alpha.-hydroxyalkanoyl|... Preparation of 1-n¬.omega.-amino-.alpha.-hydroxyalkanoyl|...

C - Chemistry, Metallurgy

07

H

260/230.5

C07H 15/22 (2006.01) C07H 15/236 (2006.01)

Patent

CA 1100953

ABSTRACT OF THE DISCLOSURE An improved process for the preparation of 1-N-[L-(-)- .omega.-amino-.alpha.-hydroxyalkanoyl]kanamycins comprises acylating a polysilylated kanamycin in a substantially anhydrous organic solvent with an acylating derivative an .omega.-amino- .alpha.-hydroxyalkanoic acid.

301962

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