Preparation of 1-substituted azetidine-3-ol derivatives

Details Preparation of 1-substituted azetidine-3-ol derivatives Preparation of 1-substituted azetidine-3-ol derivatives

C - Chemistry, Metallurgy

07

D

260/336.5

C07D 205/04 (2006.01)

Patent

CA 1222765

K 1946 FF ABSTRACT PREPARATION OF 1-SUBSTITUTED AZETIDINE-3-OL DERIVATIVES A process for the preparation of 1-substituted azetidin-3-ol derivatives of formula:- Image I in which R1 represents an arylmethyl group, and R2 represents a hydrogen atom or an alkyl, aryl or aralkyl group in which the alkyl moiety contains up to 8 carbon atoms, by cyclising a solution in triethylamine of an aminoalcohol of formula II Image in which Hal represents a halogen atom and R1 and R2 are as defined above. me use of such derivatives as intermediates for the preparation of azetidine-3-carboxylic acid derivatives. BK24.006

480116

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