Preparation of 1h-imidazo[4,5-c]quinolin-4-amines...

Details Preparation of 1h-imidazo[4,5-c]quinolin-4-amines... Preparation of 1h-imidazo[4,5-c]quinolin-4-amines...

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/47 (2006.01) A61P 31/12 (2006.01) C07D 221/00 (2006.01) C07D 235/00 (2006.01)

Patent

CA 2493227

The invention provides 1H-imidazo(4,5-C) quinolin-4-phthalimide intermediates useful in the synthesis of 1H-imidazo(4,5-C) quinoline-4-amines, particularly Imiquimod. The invention further provides a method for making the intermediates and a method for making 1H-imidazo (4,5-C) quinoline-4-amines via the intermediates.

L'invention concerne des intermédiaires de 1H-imidazo(4,5-C)quinoline-4-phtalimide s'utilisant dans la synthèse de 1H-imidazo[4,5-C]quinoline-4-amines, notamment l'imiquimod. L'invention concerne en outre un procédé de production d'intermédiaires et un procédé de production de 1H-imidazo[4,5-c}]quinoline-4-amines par le biais des intermédiaires.

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