Preparation of 2,3-dihydrofurans

C - Chemistry – Metallurgy – 07 – D

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C07D 307/28 (2006.01)

Patent

CA 2210934

Disclosed is a process for the preparation of 2,3-dihydrofurans from the corresponding isomeric 2,5-dihydrofurans wherein a feed mixture comprising a 2,5-dihydrofuran compound and an aldehyde selected from alkanals containing 2 to 5 carbon atoms and alkenals containing 3 or 4 carbon atoms; an epoxide selected from 1,2-epoxyalkanes containing 2 to 5 carbon atoms and 3,4-epoxy-1-butene; carbon monoxide; or a mixture of 2 or more of such aldehydes, epoxides and carbon monoxide is contacted with a supported, palladium or platinum catalyst to effect the isomerization of 2,5-dihydrofurans to 2,3-dihydrofurans.

On divulgue un procédé pour la préparation de 2,3-dihydrofuranes à partir de 2,5-dihydrofuranes isomères correspondants; dans ce procédé un mélange de départ comprenant un composé de 2,5-dihydrofurane et un aldéhyde choisi parmi les alcanals contenant 2 à 5 atomes de carbone et les alcénals contenant 3 ou 4 atomes de carbone; un époxyde choisi parmi les 1,2-époxyalcanes contenant 2 à 5 atomes de carbone et du 3,4-époxy-1-butène; du monoxyde de carbone; ou un mélange de deux de ces aldéhydes, époxydes et monoxyde de carbone ou plus, est mis en contact avec un catalyseur de palladium ou de platine sur support pour réaliser l'isomérisation des 2,5-dihydrofuranes en 2,3-dihydrofuranes.

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