Preparation of 2-hydroxymandelic acids and...

C - Chemistry – Metallurgy – 07 – C

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C07C 59/52 (2006.01) C07C 45/29 (2006.01) C07C 45/30 (2006.01) C07C 45/38 (2006.01) C07C 45/65 (2006.01) C07C 47/565 (2006.01) C07C 51/367 (2006.01)

Patent

CA 2080279

A method for the preparation of a 2-hydroxymandelic acid of the formula (see Formula I) wherein R represents an alkyl radical containing from 7 to 12 carbon atoms which comprises reacting glyoxylic acid with a phenol of the formula: (see Formula II) under acid conditions. Oxidation of the 2-hydroxymandelic acid to the corresponding 2-hydroxybenzaldehyde is also described.

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