Preparation of 3-aminomethyl-3,5,5-trimethylcyclohexylamine...

C - Chemistry – Metallurgy – 07 – C

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C07C 211/36 (2006.01) C07C 209/26 (2006.01) C07C 209/48 (2006.01) C07C 209/52 (2006.01)

Patent

CA 2255235

A process for the preparation of 3-aminomethyl-3,5,5-trimethylcyclohexylamine having a cis/trans isomer ratio of at least 70:30 by a) imination of 3-cyano-3,5,5-trimethylcyclohexanone with ammonia in the presence of an imination catalyst at temperatures of from 200 to 150°C and pressures of from 1.5 to 30 MPa to form 3-cyano-3,5,5-trimethylcyclo- hexanone imine followed by b) hydrogenation of the 3-cyano-3,5,5-4rimethylcyclohexanone imine in the presence of ammonia over a catalyst containing copper and/or a Group VIII metal at a temperature of from 80° to 160°C and under a pressure of from 5 to 30 MPa, wherein the catalytic hydrogenation of the 3-cyano-3,5,5- trimethylcyclohexanone imine is carried out in the presence of an acid used in an amount such as to give an acid number of from 0.1 to 2, based on 3-cyano-3,5,5-trimethylcyclohexanone used.

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