Preparation of 4-(4-fluorophenyl)-n-alkylnipecotinate...

Details Preparation of 4-(4-fluorophenyl)-n-alkylnipecotinate... Preparation of 4-(4-fluorophenyl)-n-alkylnipecotinate...

C - Chemistry, Metallurgy

07

D

C07D 211/60 (2006.01) C07D 405/12 (2006.01)

Patent

CA 2386981

A process for the industrial scale manufacture of 4-(4-fluorophenyl)-N- alkylnipecotinate esters by the addition of 4-fluorophenylmagnesium halide in tetrahydrofuran to 3,4-unsaturated-3-piperidine esters.

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