Preparation of a hepatitis b immune globulin and use thereof...

Details Preparation of a hepatitis b immune globulin and use thereof... Preparation of a hepatitis b immune globulin and use thereof...

A - Human Necessities

61

K

167/139

A61K 39/395 (2006.01) C07K 16/08 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1069822

PREPARATION OF A HEPATITIS B IMMUNE GLOBULIN AND USE THEREOF AS A PROPHYLACTIC MATERIAL ABSTRACT OF THE DISCLOSURE A method for producing a novel immunizing agent is described. The immunizing agent is anti-HBS gamma globulin essentially free of fibrinogen, plasminogen, 19 S globulin and lipids found to be effective in immunizing against hepatitis B virus disease. The method of producing this material involves fractionation of human plasma utilizing selective solvent and control of pH, temperature and ionic strength.

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