Preparation of a recombinant protein in a prokaryotic host cell

Details Preparation of a recombinant protein in a prokaryotic host cell Preparation of a recombinant protein in a prokaryotic host cell

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) C07K 14/61 (2006.01) C07K 19/00 (2006.01) C12N 15/18 (2006.01) C12N 15/55 (2006.01) C12N 15/67 (2006.01) C12N 15/74 (2006.01) C12P 21/02 (2006.01) C12N 9/20 (2006.01)

Patent

CA 2414978

The invention relates to advantageous processes for preparing heterologous proteins in prokaryotic host cells by improved codon use and/or expression of tRNAs which code for codons occurring rarely in said host cell.

L'invention concerne des procédés avantageux de préparation de protéines hétérologues dans des cellules hôtes procaryotiques par l'utilisation améliorée de codon et/ou l'expression d' ARNt codant pour les codons que l'on trouve rarement dans ladite cellule hôte.

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