C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 19/173 (2006.01) C07H 19/073 (2006.01)
Patent
CA 2735079
The present invention provides (i) a process for preparing a 2-deoxy-2-fluro-2- methyl-D- ribonolactone derivative, (ii) conversion of the lactone to nucleosides with potent anti-HCV activity, and their analogues, and (iii) a method to prepare the anti-HCV nucleosides containing the 2-deoxy-2-fluoro-2-C-methyl-.beta.-D-ribofuranosyl nucleosides from a preformed, preferably naturally-occurring, nucleoside.
Chun Byoung-Kwon
Du Jinfa
Shi Junxing
Stec Wojciech
Wang Peiyuan
Pharmasset Inc.
Ridout & Maybee Llp
LandOfFree
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