Preparation of .alpha.1 antichymotrypsin

Details Preparation of .alpha.1 antichymotrypsin Preparation of .alpha.1 antichymotrypsin

C - Chemistry, Metallurgy

07

K

C07K 14/81 (2006.01) A61K 38/57 (2006.01) C07K 1/18 (2006.01)

Patent

CA 2154982

Human .alpha.1-antichymotrypsin (ACT) can be purified from solutions containing human .alpha.1-proteinase inhibitor (PI) and antithrombin III (AT-III) using chromatography adsorption steps at carefully controlled pH and conductivity. The separated ACT retains in vitro inhibitory capacity and has potential therapeutic use.

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