Preparation of amine derivatives

C - Chemistry – Metallurgy – 07 – C

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260/367.3, 260/6

C07C 323/27 (2006.01) C07D 307/52 (2006.01)

Patent

CA 1308732

A B S T R A C T This invention relates to a process for the preparation of a compound containing an -NHC(=CHNO2)NHCH3. The process comprises reacting an N-methyl derviative of the general formula (II): Image (II) wherein R1 is a C1-4 alkyl group, with a suitable amine. The resulting compounds are useful histamine H2-antagonists.

590391

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