Preparation of amino acid amides

Details Preparation of amino acid amides Preparation of amino acid amides

C - Chemistry, Metallurgy

07

D

C07D 207/277 (2006.01) C07C 231/02 (2006.01) C07C 231/12 (2006.01) C07C 237/06 (2006.01) C07D 207/16 (2006.01) C07D 207/27 (2006.01)

Patent

CA 2497062

A process for making amino acid amides, comprising reacting an amino acid, or acid salt of an amino acid, with a halogenating agent, or with a substance that reacts with carboxylic acids to form a leaving group, to form an intermediate, then reacting the intermediate with ammonia. When the amino acid or acid salt is enantiomerically pure, the amide will be a stereoisomer. An amide made by the process can be used to form levetiracetam.

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