Preparation of aminocyclopentanealkenoic acids

C - Chemistry – Metallurgy – 07 – D

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260/247.1, 260/2

C07D 295/14 (2006.01) C07D 295/155 (2006.01) C07D 413/12 (2006.01) C07F 7/08 (2006.01)

Patent

CA 1194473

ABSTRACT OF THE DISCLOSURE A process is described for the preparation of compounds of the formula (l) Image (1) (and their salts and hydrates) in which: W is alkylene X is cis or trans -CH=CH-; Y is a saturated heterocyçlic amino group having 5-8 ring members; and R2 is C3-6 alkenyl (optionally substituted), C1-12 alkyl, or substituted or unsubstituted phenylalkyl, thienylalkyl, furanylalkyl, biphenyl- alkyl or naphthylalkyl. The process comprises hydrolysing in ester of the acid (1).

414398

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