Preparation of an antidepressant

C - Chemistry – Metallurgy – 07 – D

Patent

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260/241.35

C07D 223/28 (2006.01)

Patent

CA 1079274

PREPARATION OF AN ANTIDEPRESSANT ABSTRACT OF THE DISCLOSURE The present invention relates to a new and improved method for the preparation of the hydrochloride of 4`-chloro-2- -{/3-(10,11-dihydro-5H-dibenz(b,f-)azepinyl-(5))-prropyl/-methyl- -amino} -acetophenone, in the following called lofepramine hydrochloride. In the following, the free base is referred to as lofepramine. - 1 -

255508

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