A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/127 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2652222
A method of preparing an antibody- or antibody fragment-targeted cationic immunoliposome or polymer complex comprises the steps of (a) preparing an antibody or antibody fragment; (b) mixing said antibody or antibody fragment with a cationic liposome to form a cationic immunoliposome or with a cationic polymer to form a polyplex; and (c) mixing said cationic immunoliposome or said polyplex with a therapeutic or diagnostic agent to form said antibody- or antibody fragment-targeted cationic immunoliposome or polymer complex.
La présente invention concerne un procédé de préparation d'un immunoliposome cationique, ou d'un complexe polymérique cationique, ciblé sur un anticorps ou sur des fragments d'anticorps, le procédé comportant les étapes qui consistent à (a) préparer un anticorps ou un fragment d'anticorps, (b) mélanger ledit anticorps ou ledit fragment d'anticorps avec un liposome cationique de façon à former un immunoliposome cationique ou avec un polymère cationique de façon à former un polyplexe, et (c) mélanger ledit immunoliposome cationique ou ledit polyplexe avec un agent thérapeutique ou diagnostique de façon à former ledit immunoliposome cationique, ou ledit complexe polymérique cationique, ciblé sur un anticorps ou sur des fragments d'anticorps.
Chang Esther H.
Pirollo Kathleen F.
Georgetown University
Mbm Intellectual Property Law Llp
LandOfFree
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