C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/88 (2006.01) A61K 9/00 (2006.01) A61K 31/137 (2006.01) A61K 31/235 (2006.01) A61K 31/7072 (2006.01) A61K 31/713 (2006.01) A61K 39/395 (2006.01) A61K 47/24 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01) C12P 21/08 (2006.01)
Patent
CA 2568354
The present invention provides methods of preparing an antibody- or antibody fragment-targeted cationic immunoliposome or polymer complex comprising (a) preparing an antibody or antibody fragment; (b) mixing said antibody or antibody fragment with a cationic liposome to form a cationic immunoliposome or with a cationic polymer to form a polyplex; and (c) mixing said cationic immunoliposome or said polyplex with a therapeutic or diagnostic agent to form said antibody- or antibody fragment-targeted cationic immunoliposome or polymer complex. The present invention also provides cationic immunoliposome or polymer complexes produced by such methods and compositions comprising such complexes. The present invention also provides methods for treating various diseases and disorders, including cancers, by administering the complexes and compositions of the invention to a patient.
Chang Esther H.
Pirollo Kathleen F.
Georgetown University
Osler Hoskin & Harcourt Llp
LandOfFree
Preparation of antibody or an antibody fragment-targeted... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Preparation of antibody or an antibody fragment-targeted..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Preparation of antibody or an antibody fragment-targeted... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1647388