Preparation of antigens of and of vaccines for the virus of...

Details Preparation of antigens of and of vaccines for the virus of... Preparation of antigens of and of vaccines for the virus of...

C - Chemistry, Metallurgy

12

N

C12N 7/04 (2006.01) A61K 39/12 (2006.01) A61K 39/295 (2006.01) C07K 14/115 (2006.01) C12N 7/02 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2127991

(57) Abstract Process for isolating the Mystery Disease virus consisting in taking the organs of sick or infected pigs, grinding the sample and passing the fluid floating on the surface onto heterologous or homologous cells, then collecting said fluid For the industrial production of the Mystery Disease virus, the virus is cultivated on sensitive heterologous or homologous cells. Purified Mystery Disease viral antigen preparations comprise living viral particles, attenuated or not, or inactivated particles or sub-unit antigens or antigens expressed by genetic recombination from isolated virus genes. The invention also concerns vaccines containing a vac- cinating quantity of such antigen.

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