Preparation of antigens of and of vaccines for the virus of...

Details Preparation of antigens of and of vaccines for the virus of... Preparation of antigens of and of vaccines for the virus of...

C - Chemistry, Metallurgy

12

N

C12N 7/04 (2006.01) A61K 39/145 (2006.01) A61K 39/155 (2006.01) C12N 7/00 (2006.01) C12N 7/02 (2006.01) C12N 15/45 (2006.01)

Patent

CA 2081638

ABSTRACT Preparation of antigens of and of vaccines for the virus of Mystery Disease, antigens and vaccines obtained for the prevention of this disease. The process for isolating the virus of Mystery Disease comprises taking samples from organs of sick or infected pigs, milling the samples and passing the milling supernatant through sensitive heterologous or homologous cells and then harvesting the supernatant. For the industrial production of the virus of Mystery Disease, the virus is cultured in sensitive heterologous or homologous cells. The preparations of purified viral antigen of Mystery Disease comprise living viral particles, optionally atrtenuated, or inactivated particles or subunit antigens or antigens expressed by genetic recombination from genes of the isolated virus. vaccines containing a vaccinating quantity of such an antigen.

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